Download e-book for iPad: A Colour Handbook of Oral Medicine by Richard C.K. Jordan, Michael A.O. Lewis

By Richard C.K. Jordan, Michael A.O. Lewis

ISBN-10: 184076032X

ISBN-13: 9781840760323

ISBN-10: 1840765569

ISBN-13: 9781840765564

A accomplished advisor to prognosis and therapy of oral problems;superb color illustrations built-in all through - combining some great benefits of an atlas with a quick text/reference;symptoms-based approach;one in step with web page or web page spread.


A complete consultant to analysis and therapy of oral difficulties; fabulous color illustrations built-in all through - combining the benefits of an atlas with a brief text/reference; symptoms-based Read more...

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Example text

Careful HLA matching of BMT donor and recipient is important. Modulation of the immune response in the recipient is necessary, using immunosuppressive medications such as ciclosporin (cyclosporin). Psoralen and ultra-violet A (PUVA) therapy is helpful for cutaneous lesions. Suspected candidosis (candidiasis) needs to be confirmed microbiologically and treated appropriately. Xerostomia is managed symptomatically with salivary substitutes and burning can be relieved using topical anesthetic agents.

The patient is likely to describe their problem as ‘the lining of the mouth peeling off’. DIAGNOSIS Biopsy tissue, sent for histopathologic analysis, should be examined for evidence of a submucosal split (110). Separate biopsy material should be sent on ice or in Michel’s medium for direct immunofluorescence (IF) studies that will show a linear deposition of IgG and C3 along the basement membrane (111). Indirect IF, using the patient’s serum, is often negative and therefore of questionable additional value if direct IF is performed.

Confirmation of the presence of HSV can be made by isolation from a swab in tissue culture or the use of immunofluorescence on a smear of a recent lesion. MANAGEMENT In many cases no active treatment is indicated but the patient should be warned about the infectivity of the lesion. The use of topical aciclovir (acyclovir) or penciclovir as early as possible can reduce the duration of herpes labialis. A sunscreen applied to the lips can also be effective in reducing the frequency of sunlightinduced recurrences.

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A Colour Handbook of Oral Medicine by Richard C.K. Jordan, Michael A.O. Lewis

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